Particle Characterization System Uses Raman Spectroscopy

Malvern Instruments has launched the Morphologi G3-ID particle characterization system to the global market. The system combines automated particle imaging with the chemical identification of individual particles using Raman spectroscopy. This fully automated system measures particle size, shape and chemical identity in a single platform.

The Morphologi G3-ID is suitable for solving complex particle characterization problems where particle size and shape do not provide sufficient information. The recent early access program was designed to enable users to explore specific applications and to allow full optimization of the product features. The system can help determine component-specific particle properties of mixtures and blends, such as the particle size of drug ingredients in nasal sprays and asthma inhalers, and in the identification of unknown or suspicious particles in injectable or parenteral products.

The Morphologi G3-ID was designed to meet a wide variety of needs and to enable all users, from particle characterization scientists with limited spectroscopy experience right through to experienced spectroscopists, to gain an in-depth understanding of particulate samples. SOP operation takes the user from integrated sample dispersion for dry powders through to size, shape and chemical analysis with automatic selection, targeting and chemical classification of thousands of individual particles. Measurements can be made on dry powders, suspensions and membrane filters.