EMD Millipore, the life science business of Merck KGaA, introduces a new technology that compacts dry powder cell culture media into granules, accelerating solubility and improving flowability and handling, according to the company. The technology is water- and additive-free and applies compression force to EMD Millipore's homogenous dry powder media, fixing the homogeneity in place and creating granules several millimeters in size. The process does not alter the media's amino acid or vitamin composition, and leaves intact the physicochemical parameters of dissolved media and feeds, preserving the media's ability to support cell growth and productivity.
Compaction significantly minimizes dust formation, improving media handling as well as cleanliness within the production area, according to the company. The higher density of compacted media reportedly allows for faster dissolution, while improved product flowability facilitates the dosing and mixing processes and limits media caking.
EMD Millipore will use compaction technology to produce customized cell culture media formulations for customers' specific process needs. The company also plans to use compaction technology to enhance its established portfolio of cell culture media products.
